Yajie Yin Selected Research

ONC206

1/2022	ONC206 has anti-tumorigenic effects in human ovarian cancer cells and in a transgenic mouse model of high-grade serous ovarian cancer.
1/2021	Highly potent dopamine receptor D2 antagonist ONC206 demonstrates anti-tumorigenic activity in endometrial cancer.
1/2020	ONC206, an Imipridone Derivative, Induces Cell Death Through Activation of the Integrated Stress Response in Serous Endometrial Cancer In Vitro.

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Yajie Yin Research Topics

Disease

15	Neoplasms (Cancer) 03/2022 - 11/2017
9	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 09/2016
6	Endometrial Neoplasms (Endometrial Cancer) 02/2021 - 01/2018
4	Obesity 02/2021 - 01/2018
2	Hematologic Neoplasms (Hematological Malignancy) 02/2021 - 01/2021
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2021
1	Hypersensitivity (Allergy) 01/2020
1	Immediate Hypersensitivity 01/2020
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2019
1	Neoplasm Metastasis (Metastasis) 01/2018
1	Carcinoma (Carcinomatosis) 01/2018
1	Glioma (Gliomas) 01/2018
1	Lactic Acidosis 11/2017
1	Type 2 Diabetes Mellitus (MODY) 11/2017
1	Weight Loss (Weight Reduction) 09/2016

Drug/Important Bio-Agent (IBA)

6	TIC10 compoundIBA 01/2022 - 01/2018
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 01/2020
4	Metformin (Glucophage)FDA LinkGeneric 01/2021 - 09/2016
3	ONC206IBA 01/2022 - 01/2020
3	Dopamine Receptors (Dopamine Receptor)IBA 02/2021 - 01/2020
3	BiguanidesIBA 01/2021 - 09/2016
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 01/2021
2	LigandsIBA 01/2022 - 01/2021
2	Peptide Hydrolases (Proteases)FDA Link 01/2022 - 01/2022
2	LipidsIBA 02/2021 - 01/2019
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 09/2017
1	C-Reactive ProteinIBA 03/2022
1	Biomarkers (Surrogate Marker)IBA 03/2022
1	AutoantigensIBA 11/2021
1	Messenger RNA (mRNA)IBA 02/2021
1	Biological ProductsIBA 01/2021
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2020
1	Docosahexaenoic AcidsIBA 01/2020
1	Pharmaceutical PreparationsIBA 01/2020
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2020
1	Fish OilsIBA 01/2020
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2020
1	ProdrugsIBA 01/2020
1	cremophor ELIBA 01/2020
1	Generic DrugsIBA 01/2019
1	Estrogen Receptor alphaIBA 01/2018
1	Carbonic Anhydrase IXIBA 01/2018
1	IsoflavonesIBA 01/2018
1	IsoenzymesIBA 01/2018
1	Topiramate (Topamax)FDA LinkGeneric 01/2018
1	Estrogens (Estrogen)FDA Link 01/2018
1	GenisteinIBA 01/2018
1	Carbonic Anhydrases (Carbonic Anhydrase)IBA 01/2018
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2018
1	Phenformin (Fenformin)IBA 11/2017
1	Caspase 3 (Caspase-3)IBA 11/2017
1	Glutamine (L-Glutamine)FDA Link 09/2017
1	Aminooxyacetic AcidIBA 09/2017
1	Adenosine Triphosphate (ATP)IBA 09/2017
1	Pyruvic Acid (Pyruvate)IBA 09/2017
1	Calcium Carbonate (Limestone)FDA Link 09/2016

Therapy/Procedure

2	Fat-Restricted Diet (Diet, Fat Restricted) 01/2022 - 02/2021
2	Therapeutics 01/2020 - 01/2020